Insomnia, Related Problems and Coping Strategies Among Primigravida and Multigravida Mothers

Background: Insomnia is a typical complaint during pregnancy. Hormonal alterations, physiological changes during early pregnancy, and the enlargement of the foetus during late pregnancy contribute to disrupted sleep. Nursing interventions to identify sleep deficits and promote sleep are required at all stages of the maternity cycle. Methods: Insomnia, related problems and coping strategies were assessed using a structured Questionnaire of purposive sample of 50 Primigravida and 50 Multigravida Mothers attending OBG unit at HSK hospital and research centre, Bagalkot, Karnataka. Data were analyzed using descriptive and inferential statistics. Results: The result depicts that the majority of primigravida mothers (92%) experienced moderate and 8% experienced severe insomnia, 94% moderate, 4% mild and 2% experienced severe insomnia-related problems, 84% followed average, 12% good and 4% followed poor coping strategies, whereas, majority of Multigravida mothers (90%) experienced mild and 10% experienced moderate insomnia, 82% moderate and 18% experienced mild degree insomnia related problems, 92% followed average, 6% good and 2% followed poor coping strategies. There is a significant difference between primigravida mothers' insomnia, related problems and coping strategies and that of multigravida mothers. There was an irrelevant association found between insomnia scores of Primigravida and Multigravida mothers with socio-demographic variables. Conclusion: The overall study findings depicted that the mean percentage scores of insomnia of primigravida mothers (49.33%) was comparatively higher than the mean percentage scores of multigravida mothers (16.33%). Hence it was concluded that primigravida mothers has experienced more insomnia than compared to multigravida mothers.

Immunohistochemical Evaluation of Calretinin in Ameloblastoma, Odontogenic keratocyst and Dentigerous Cyst

Background: Calretinin plays an important role in calcium signalling and naturally expressed in nervous tissues. Various stud- ies suggest that calretinin may involve in amelogenesis. Calretinin also seems to have role in tumorigenesis since it regulates apoptosis. Aim: To find out whether there is any variation in expression of calretinin in Ameloblastoma, Odontogenic keratocyst and Dentigerous cyst. Materials & Methods: A total of 50 samples each from Ameloblastoma, odontogenic keratocyst and Dentigerous cyst were retrospectively studied. The immunohistochemical expression of calretinin was assessed by using calretinin antibody. Results: Chi square test was used to compare categorical parameters between groups. Kruskal Wallis Test and Mann-Whitney U Test were carried out to compare quantitative parameters among the groups. Statistically, significant values were obtained when comparing the immunohistochemical expression of calretinin in various odontogenic lesions studied and it was highest in ameloblastoma followed by OKC. None of the cases of dentigerous cyst were immunopositive for calretinin. Conclusion: There was statistically significant variation in the expression of calretinin among ameloblastoma, OKC and dentig- erous cyst and it contributes to the aggressiveness of those lesions.

Expression of Ki67 as Potential Biomarker in Oral Submucous Fibrosis: An Immunohistochemical Study

Background: Oral submucous fibrosis (OSMF) is a potentially malignant disorder (PMD) known to transform into oral cancer. One of the important hallmarks of malignant transformation is the uncontrolled growth rate, commonly reflected as increased cell proliferation which can be significantly detected by proliferative markers such as a high Ki?67 index. Aim: The aim of this study is to evaluate the degree and pattern of expression of Ki67 in OSMF, oral squamous cell carcinoma (OSCC) and in normal mucosal (NOM) patients and to correlate the Ki67 expression with clinical and histological grading of OSMF and OSCC patient. Materials and Methods: A prospective cross?sectional study was conducted over a duration of two years. An immunohistochemical study was performed for Ki76 expression on 35 cases of OSMF, 10 cases of OSCC and 10 normal mucosal patients. Statistical Analysis: Data were analysed using SPSS version 21. Chi?squared test was used to analyse the differences between the intensity levels in OSMF, OSCC and NOM. Results: Expression of Ki67 was significantly higher in OSMF than that of NOM samples but less than that of OSCC samples. Expression of Ki67 increased with increasing grade of clinical and histological stages. Conclusion: The study demonstrated a high incidence of Ki67 overexpression in OSMF and OSCC and showed a correlation between clinical and histological grading of OSMF and OSCC. Identification of high?risk oral PMDs and intervention at premalignant stages could constitute one of the key steps in reducing the mortality, morbidity and cost of treatment associated with malignant transformation of these diseases

Accuracy of digital mammography, ultrasound and MRI in predicting the pathological complete response and residual tumor size of breast cancer after completion of neoadjuvant chemotherapy

Background: Neoadjuvant chemotherapy (NACT) is the standard of care for the treatment of locally advanced or non-metastatic breast cancer, which may increase the chances of breast conservative surgery (BCS) in place of radical mastectomy without compromising on the overall survival. The aim of this study was to evaluate the accuracy of mammography (MG), ultrasound (US), and magnetic resonance imaging (MRI) in predicting the complete response and to assess the extent of residual breast cancer in women treated with NACT. Materials and Methods: Fifty-six consecutive patients with stage II or III breast cancer, who underwent imaging evaluation of breast with digital mammogram, US, and MRI after NACT and before the breast surgery, were included in the study. For each patient, pathologic complete response (pCR) or residual tumor (non-pCR) was predicted and the maximum extent of the residual tumor was measured on each imaging modality. These measurements were subsequently compared with the final histopathology results. Results: Of 56 patients, 22 showed pCR with MRI having better accuracy for predicting complete response than the MG and US (area under the receiver operating characteristic curve: 0.86, 0.68, and 0.65, respectively; p = 0.0001 for MRI; p = 0.06 for MG, and p = 0.02 for US). The sensitivity of MRI for detecting pCR was 72.7%; specificity and positive predictive value were 100%. For pathological residual tumor, the size measured on MRI showed significantly higher correlation with the pathologic size (correlation coefficient, r = 0.786), than the MG (r = 0.293) and US (r = 0.508) with P < 0.05. Conclusions: Accuracy of MRI for predicting pathological complete response was significantly higher than the MG and US. Pathologic residual tumor size was also more precisely reflected by the longest tumor dimension on MRI with the strong positive correlation coefficient

Carbohydrate profiling & glycaemic indices of selected traditional Indian foods

Background & objectives: Consumption of high glycaemic index (GI) food is associated with a high risk for diabetes. There is a felt need to understand the GI of common Indian traditional foods using standard GI protocols. The present study was aimed to analyse the carbohydrate profile of common traditional Indian food preparation and to determine their GI using standardized protocols. Methods: Twelve food preparations made of millets, wheat, maize and pulses were evaluated for nutrient composition including detailed carbohydrate profiling and tested for GI in healthy volunteers using standard methodology. Capillary blood glucose responses for the test foods containing 50 g available carbohydrates were recorded and compared to the reference food (50 g glucose). GI was calculated from the incremental area under the curve (IUAC) for the test and reference foods. Results: Available carbohydrate content of the food preparations ranged between 13.6 and 49.4 g per cent. Maize roti showed the highest total dietary fibre (7.5 g%). White chick pea ‘sundal’ showed highest resistant starch content (3.95 g%). Amongst the 12 test foods, five fell in the high GI category (finger millet balls, sorghum, pearl millet and maize roti), four in the medium GI category (sorghum idli, wheat dosa, methi roti and adai) and three in the low GI category (broken wheat upma, white peas sundal and white chick peas sundal). Interpretation & conclusions: Merely being a whole grain-based food does not qualify for a lower GI. The method of processing, food structural integrity and preparation could influence the GI. The type and quality of fibre are important than the quantity of fibre alone. Judicious planning of accompaniments using low GI legumes may favourably modify the glycaemic response to high GI foods in a meal.

Preparing for the silver boom: A falls prevention tool for older adults in the emergency department

Geriatric falls presenting to the emergency department (ED) are rising due to our rapidly ageing population. As part of a group of geriatric-focused emergency medicine practitioners, we describe a multidisciplinary falls prevention tool using the acronym.

Can platelet-rich plasma injections provide better pain relief and functional outcomes in persons with common shoulder diseases: a meta-analysis of randomized controlled trials

To evaluate the efficacy of autologous platelet-rich plasma (PRP) injections in the treatment of common shoulder diseases. Methods: The PubMed, Medline, and Central databases and trial registries were searched from their inception to October 2020 for randomized controlled trials of autologous PRP injections for shoulder diseases versus placebo or any control intervention. Preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines were followed in the selection, analysis, and reporting of findings. The primary outcome was pain intensity (visual analog scale), and secondary outcomes were changes in function and quality of life (QoL). Results: A total of 17 randomized controlled trials of PRP versus control were analyzed. From 8–12 weeks to ≥1 year, PRP injections were associated with better pain relief and functional outcomes than control interventions. PRP injections were also associated with greater QoL, with an effect size of 2.61 (95% confidence interval, 2.01–14.17) at medium-term follow-up. Compared with placebo and corticosteroid injections, PRP injections provided better pain relief and functional improvement. In subgroup analyses, trials in which PRP was prepared by the double centrifugation technique, the platelet concentration in the PRP was enriched ≥5 times, leucocyte-rich PRP was used, or an activating agent was used before application reported the most effective pain relief at 6–7 months. Conclusions: PRP injections could provide better pain relief and functional outcomes than other treatments for persons presenting with common shoulder diseases. PRP injections have a greater capacity to improve shoulder-related QoL than other interventions.

Threatening Health Impacts and Challenging Life of Sanitary Workers

The term sanitation refers to adequate treatment and disposal of human excreta and sewage, and provide clean drinking water. The aim of sanitary system is protecting human health by providing safe and clean environment. It helps to prevent transmission of diseases which are spreading through faecal-oral route. Sanitary workers are protecting the society from diseases such as diarrhoea, ascariasis, cholera, hepatitis, poliomyelitis, schistosomiasis and trachoma with their effective services.Sanitary services are given by the sanitary workers for the betterment of human health. Sanitary workers are doing the work such as sweeping streets, collecting waste from house to house and streets, latrine or pit cleaning, cleaning school toilets, public toilets, toilets of municipalities, government and private offices, operating waste collecting trucks, management of faecal sludge, desludging the septic tank, cleaning sewer, cleaning manholes, cleaning sewage treatment plants and handling waste water and sludge at sewage treatment plants.Sanitary workers are the key persons responsible for cleanliness of the country. At the same time, they are facing many challenges such as (i) issues related to their health and safety: cuts, injuries, musculoskeletal problems, respiratory problems, gastro intestinal problems and infectious diseases like gastroenteritis, diarrhoea, cryptosporidiosis, giardiasis, hepatitis A, hepatitis B, leptospirosis, salmonellosis, typhoid fever and tetanus.; (ii) legal and institutional issues: poor enforcement of law, lack of standard operating procedures, poor legal protection and workers safety which is influenced by the availability of equipment and materials used for doing the work and also by customers and employers; (iii) insecurity in financial status and social issues; social stigma like intergenerational discrimination.Sanitary workers are not concentrating on their own health and nutritional status due to lake of awareness. There is a need to enrich the knowledge of workers regarding prevention of health problems, protection from health issues and promotion of their health. The employer has to ensure that workers have undergone training before placement in the job and also, they must be provided with proper guidelines. Workers must get adequate facilities in the working area. Sanitary workers must be provided with personal protective equipment and insisted to use it properly. Regular medical check-up, vaccination and follow up are very important to protect the sanitary workers.

Review on Pharmacoscintigraphy

Pharmacoscintigraphy is a non-invasive technique for determining the fate of drugs after administration into humans. Collecting valuable information through the pharmacoscintigraphyabout absorption and release mechanisms of drugs from formulations, and thus proving to be an invaluable tool in developing newer and more effective formulations. Such studies can be used to determine the behavior of drugs, formulation as well as diagnostic agents that are administered. In this technique, radiolabelled formulations are administered to patients by their intended route of administration. Their transit through the body is monitored using sophisticated imaging cameras. Since the amount of radiotracer that is used is very low, this is a safe, efficient, and accurate method for studying the behavior of drugs in the human body. Preclinical studies of newer drugs have successfully been carried out using the pharmacoscintigraphic technique

Super Porous Hydrogels: A Review

Super porous hydrogels (SPHs) basically developed initially create as a novel drug delivery system to absorb and continue to hold the drugs in the gastric medium which allows absorption in stomach and upper part of the gastrointestinal tract. These systems get swollen in the stomach instantly and in the harsh stomach environment they maintain their integrity, while the pharmaceutical active ingredient is being released. Instant and fast swelling property of hydrogel is based on water absorption through open porous structure by capillary force. SPHs have the poor mechanical strength which has got over by developing the second-generation SPH composites (SPHCs) and the third-generation SPH hybrids (SPHHs). The present review has been focused on the preparation, characterization and application of SPHs

A Comparative Study of Bronchial Washing and Brushing, with Bronchial Biopsy

Lung cancer is the most common cancer around the world and is associated with significant mortality. Smoking is the most important risk factor. Screening and early diagnosis has significant role in initiating treatment and reducing mortality rates. Also, definite histological subtyping is mandatory for newer therapeutic strategies. Over the past decades, screening for lung cancer has evolved with the advent of bronchoscopy and cytological evaluation. Even though various biomarkers of lung cancer are in study, cytological evaluation of bronchial brushing and washing has become a useful and cost-effective screening method for lung cancer and is widely used all around the world.METHODSIt was a comparative cross-sectional study conducted in the Department of Pathology, Government Medical College, Thrissur, from 1-1-2017 to 30-6-2018. Bronchial washing and brushing specimens received along with biopsy, which are suspicious for bronchogenic carcinoma were included in the study. Sample size was 82. Cytological smears are stained with Giemsa staining and Papanicolaou’s staining. Biopsy specimens are stained with haematoxylin and eosin staining after processing.RESULTSMajority of patients were in the age group of 60 – 79 years (75.6%), and mean age was 64.14 years. Cigarette smoking was seen in 55 patients (67.1%). Out of the 82 cases, 46 cases (56%) were squamous cell carcinoma, 14 cases (17%) were adenocarcinoma, 15 cases (18.3%) were non-small cell carcinoma- NOS, 7 cases (8.6%) were small cell carcinoma. Positivity rates for malignancy with brushing was 52.4%, washing 19.5% and combined 54.9%. Bronchial brushing had a sensitivity of 19.6% in squamous cell carcinoma, 28.6% in adenocarcinoma, 26.7% in non-small cell carcinoma (NSCLC)-NOS, 28.6% in small cell carcinoma (SCLC). Compared to bronchial brushing, the sensitivity of bronchial washing was lower and combination of washing with brushing yielded no additive effects except in adenocarcinoma cases.CONCLUSIONSAmong routinely employed cytological techniques in our centre for a diagnosis of bronchogenic carcinoma, bronchial brushing has higher sensitivity and specificity than bronchial washing. Even though the combination of both cytological techniques yielded not much difference in sensitivity and specificity than brushing alone, usefulness of bronchial washing was evident in adenocarcinomas. Therefore, bronchial brushing, washing and biopsy should be done in the evaluation of suspicious bronchogenic carcinoma and major importance in the processing, evaluation and analysis of brushing will be useful in better cytological diagnosis.

Knowledge, Attitude and Practice about Male Infertility among Men and Women in the Field Practice Area of a Tertiary Care Teaching Hospital

Background: Infertility causes distress among 15% of global population. The common myth is that women contribute to a higher level for this data than men.Purpose: Hence a questionnaire study was done in the field area of a tertiary care teaching hospital and research centre. Methods: A total of 100 male and 100 female participants of age group ≥18 years of age between the months of May 2018 and August 2018. This study was done to describe the knowledge attitude and perception and myths prevalent in the study population.Results: The analysis revealed that there is an exponential increase in the knowledge aspect regarding the common causes of infertility and also women are not considered as the sole reason for infertility anymore. The attitude towards infertility as a disease also has changed to the better. The people have exhibited that the common folk has realized that allopathy helps better in curing infertility than other quacks. Conclusion: Furthermore the study participants have recognized that infertility is not ground for divorce. Also the familiarity to IVF and adoption has expanded

Paroxysmal hypertension with reversible posterior leukoencephalopathy syndrome in a child: an unresolved riddle

Nine year old girl was presented with paroxysmal episodes of hypertensive emergency. She was asymptomatic with normal blood pressure without antihypertensives in between the episodes. MRI brain was suggestive of reversible posterior leukoencephalopathy.' Acute episodes were managed with IV labetalol infusion and amlodipine. She was evaluated extensively to find out the etiology of hypertension. Cardiac and renal causes were ruled out. Work up for pheochromocytoma, hyperaldosteronism, porphyria and vasculitis were negative. The case is reported in view of the rare presentation and the leukoencephalopathy noted in this case.

Seroprevalence of syphilis in human immunodeficiency virus patients

Background: Syphilis is a sexually transmitted infection caused by, Treponema pallidum. Syphilis facilitates the transmission and acquisition of human immunodeficiency virus (HIV) and causes transient increase in the viral load. Sexually transmitted infections (STI) are 3-5 times more likely to acquire HIV infection, if exposed to the virus through sexual contact. Aim of the study was to estimate the seroprevalence of Syphilis in HIV patients.Methods: A total of 920 blood samples were collected from HIV patients attending ART (Antiretroviral therapy) centre and were tested for Syphilis by using Rapid Plasma Reagin (RPR) and Treponema pallidum Hemagglutination Assay (TPHA). A total of 100 HIV non-reactive individuals were taken as a control group.Results: Out of 920 samples, 102 (11.1%) were positive for Syphilis. Out of 102 Syphilis seropositive patients, males (76.5%) were more commonly affected in age group of 21-40 years. Both RPR and TPHA were reactive in 46% of cases and only TPHA reactive in 53.9% of cases. Out of 100 HIV non-reactive patients, 5% of patients are reactive for Syphilis.Conclusions: In the present study, prevalence of Syphilis was more in HIV patients compared to HIV non-reactive persons. Persons with HIV infection acquired through sexual route should be screened for Syphilis by one nonspecific test along with specific test to confirm the diagnosis. This will help in proper management of the patients having Syphilis and HIV co-infection.

Ultrasound Guided Interscalene Block & Shoulder Block for Postoperative Analgesia for Shoulder Surgeries

Shoulder arthroscopic surgeries can produce intense postoperative pain. Interscalene block provides good analgesia after shoulder surgery, but concerns over its associated risks have prompted the search for alternatives. Suprascapular block along with axillary nerve block was recently proposed as an alternative to interscalene block, but evidence of its comparative efficacy is conflicting. The aim of our study was to compare suprascapular and axillary nerve blocks with interscalene block in shoulder surgery for postoperative analgesia. Methods: A total of 76 patients scheduled for shoulder arthroscopic surgery were equally divided into two groups of 38patients each: Interscalene (ISB) group and suprascapular with axillary nerve (SHB) group. Both the nerve block was achieved by both ultrasound and nerve stimulator guidance. Visual analogue scale score was evaluated at 1, 4, 6, 12, and 24 h postoperatively. The time to first analgesia request, total analgesic requirement for 24 hr postoperatively, patient satisfaction, and any complications were recorded. Results: SHB provided equivalent analgesia to ISB in terms of post operative VAS scores.Time to 1st analgesia request was 7.2±1.3 hr in ISB group and 5.9±1.2 hr in SHB group which was not statistically significant.Patient satisfaction scores were significantly higher in SHB group compared to ISB group. Complication like subjective dyspnea and weakness of arm was significantly higher in ISB group compared to SHB group. Conclusions: SHB was as effective as ISB for postoperative pain relief but with fewer complications due to selective blockade of suprascapular and axillary nerve.

Study of Colistin Sensitivity Pattern of Pseudomonas Aeruginosa in a Tertiary Care Hospital

Introduction: Pseudomonas is an invasive organism thatcauses severe Hospital Acquired Infections in immunecompromised hosts and it exhibits a high degree of resistanceto broad spectrum antibiotics. In recent years Colistin is thedrug of choice for use against MDR strains. The aim wasto study the antibiotic susceptibility and Colistin sensitivitypattern of Pseudomonas isolates from various samples.Material and methods: 100 Pseudomonas aeruginosaisolates from various samples (exudates, bloods and urines)were included and other isolates were excluded in the study.The samples were collected under aseptic precautions.Isolation and identification of the isolates was done as per thestandard guidelines in the lab and AST was done by KirbyBauer disc diffusion method and interpretation was done asper CLSI guidelines.Results: Out of 100 isolates, 36 were from the surgicalwards;30, 20 and 14 were from medical wards, OBG andGHCCD respectively. 83%of isolates were sensitive toColistin and 17% were resistant. MDR strains (both ESBL’sand MBL’s) were detected in 33% and out of these 15.2%were also resistant to Colistin.Conclusion: Colistin is one of the first antibiotics withsignificant activity against MDR Gram negative pathogensand its usefulness has been documented that it will be the “lastline” therapeutic drug in the 21st century. In the present studyit is showing that resistance to Colistin is also increasing,recommending regular monitoring of AST for propermanagement and to limit its use routinely

A study of patterns of adverse drug reactions in a tertiary care hospital of Andhra Pradesh, India

Background: Pharmacovigilance Programme of India (PVPI) is a step towards participation in WHO programme for International Drug Safety Monitoring. Pharmacovigilance (PV) system is an integral part of drug therapy, which helps in detection, monitoring and designing strategies to minimize the occurrence of Adverse Drug Reaction (ADRs). The present study is done to study the patterns of ADRs in a tertiary care government hospital.Methods: A total of 327 suspected ADR reports submitted to the pharmacovigilance unit at department of pharmacology under PVPI were evaluated for a period of two years with respect to age, sex, causative drug, organ system involvement and seriousness of ADRs. The causality assessment was done using WHO assessment method.Results: Female patients experienced more (54.13%) ADRs. The highest percentage (49.24%) of ADRs were seen in age group of 18-44 years, followed by 45-60 years (33.33%). Medicine department reported the maximum number (42.20%) of ADRs. Antimicrobial agents (27.83%) were the commonest group of drugs causing ADRs, followed by anti psychotics (15.90%) and analgesic drugs (10.70%). Skin is the major organ system affected (30.28%). Causality assessment revealed (51.99%) of the ADRs were possible. Majority of the ADRs (79.82%) were nonserious and (20.18%) were serious requiring hospitalization. Death occurred in five patients.Conclusions: The results suggest that there is under reporting and there is a need to create awareness among health care professionals(HCP) about the importance of Pharmacovigilance .The data also helps in designing strategies for framing policies towards safer use of drugs in future.

Prevalence of oromucosal lesions in relation to tobacco habit among a Western Maharashtra population

OBJECTIVES: This study was conducted to determine the number and types of oromucosal lesions (OMLs) in relation to tobacco habits in patients who attended the outpatient department. METHODOLOGY: A total of 1730 patients visiting the Department of Oral Medicine and Radiology were interviewed and screened for tobacco habits (smoking and smokeless). Clinical oral examination was conducted with diagnostic instruments using the Color Atlas of Common Oral Diseases as a guide for diagnosis. When clinical features were not diagnostic, a biopsy was done. RESULTS: Of the 1730 outpatients, 975 (56.3% ) individuals used tobacco in one or other forms and 687 (70.4%) of these had OMLs. CONCLUSION: The results of this study provide important information on the prevalence of OMLs in patients seeking dental care. This provides baseline data for future studies on the prevalence of oral lesions in the general population.

Lipid Profile And Lipid Peroxidation In Bronchial Asthma

Background:Bronchial asthma, a chronic inflammatory condition, often triggered by allergy & oxidative stress, initi-ate lipid peroxidation& enhanced release of arachidonic acid from cell membrane. Regarding lipid profile in bronchial asthma patients many conflicting data were reported. Therefore we have conducted this study. Methodology:50 clinically diagnosed bronchial asthma cases for lipid profile and lipid peroxidation levels were compared with 50 healthy controls. Results:In our study fasting serum HDL and LDL cholesterol level of cases respectively (52.32mg/dl±3.58), (99.21mg/dl ±12.49) were found to be significantly higher when compared to controls (44.58mg/dl±2.58), (103.44mg/dl±10.55) (p-value <0.05). Mean plasma SOD level of cases (3.42 U/mL±0.74) was significantly lowered than controls (7.16 U/mL±0.52). Serum MDA level of cases (5.91nmol/L±0.88) was higher as compared to controls (3.00nmol/L±0.40). (p-value <0.001) Conclusion:Lipid profile in bronchial asthma patients (raised HDL& decreased LDL) provides some degree of protection to this patients against ischemic heart disease (IHD). But increased in lipid peroxidation as evidenced by decrease plasma SOD & raised serum MDA aggravate airway inflammation, smooth muscle contraction & increased vascular permeability

Finger millet (Eleusine coracana L.) and white rice diets elicit similar glycaemic response in Asian Indians: Evidence from a randomised clinical trial using continuous glucose monitoring

@#Introduction: Finger millet (FM) or Eleusine coracana L. is considered as a healthier cereal option, especially based on its higher dietary fibre, phytochemical and mineral contents. FM is also recommended for individuals with diabetes, as it is believed to elicit a lower glycaemic response. Methods: The glycaemic response of FM diet was evaluated and compared with white rice (WR) diets using a continuous glucose monitoring system (CGMS™) iPro 2™ among 14 healthy male and female volunteers aged 25-45 years with normal Body Mass Index (≥22.9kg/m2) in a crossover trial. They were recruited from Madras Diabetes Research Foundation volunteers registry. The participants consumed randomised iso-caloric FM or WR based diets for five consecutive days and 24 h interstitial glucose concentrations were recorded. Results: The FM diet had significantly higher dietary fibre than WR (29.9 g vs 15.8 g/1000 kcal, p<0.01) but the other macronutrients were similar. The 5-day average incremental area under the curve (IAUC) of FM diet [Mean (95% CI) = 73.6 (62.1-85.1) mg*min/dl] was not significantly different from that for WR diet [Mean (95% CI) = 78.3(67.9-88.7) mg*min/dl]. Conclusion: Both finger millet and white rice diets showed similar 24 h glycaemic responses, despite the former having higher amounts of dietary fibre. The result suggests that use of FM flour-based food preparations and decorticated FM grains to replace WR in the Indian diets offer no significant benefit with regards to 24 h glycaemic response. Studies of longer duration with larger sample size are needed to verify our findings.